Thought some of you might enjoy reading this well presented argument from Darwin (it's a bit long, so I have divided it in four parts, each numbered at the top of the post).

Darwin (1) The values of freedom and openness are crucial to understanding itself, so that civilization and public welfare now depend on them, as I argue below. These values may find their best expression in the free and open source software (FOSS) movement, and the foresightful example of FOSS developers should now be beneficially applied to many other disciplines in the context of a global and public Internet.

It is crucial that we occasionally take time to discuss the reasons _why_ we release our source code, and this is one of those occasions. There are good reasons for the freedom and openness which are characteristics of FOSS development, reasons which should receive wider attention now that they can be readily communicated to other arenas. The consequences of doing otherwise are often catastrophic.

For example, it incomprehensible that Genentech could consider withdrawing a cheap cure for blindness (ARMD) from the market.

http://lists.essential.org/pipermail/random-bits/2006-june/001374.html

The mechanism of this drug is public knowledge.

http://sourceforge.net/mailarchive/forum.php?thread_id=14183567&forum_id...

This abhorrent situation is a great example of the kind of thing that will happen if people don't get behind the values of freedom and openness that we are espousing. Please let Genentech know that you find what they are doing offensive. Publicize the mechanism so that new compounds can be obtained as replacements. For the future, continued vociferous public activism is required to prevent such outrages from occurring in the future.

It becomes clear that the compounds which come from common roots, fruits, and vegetables are a shared human heritage and the free and open source of the future. Tannins are another interesting case in point, because as molecules, and as anti-oxidents, they are similar to resveratrol (resV), and that molecular mechanism has been anchored to the public domain via a prior art declaration. It is a so-called CR-memetic, which may increase healthy human longevity by many decades. Here are some links about it.

Resveratrol mechanism posts from GNU-Darwin list http://proclus.gnu-darwin.org/gdposts.html

CR protocol for human bodies http://proclus.gnu-darwin.org/bootstrap.html

Here is some important recent news about it.

http://www.imminst.org/forum/index.php?s=&act=print&client=printer&a...

It is exciting to suppose that people can get off the pharmaceuticals that they are taking with calorie restriction or CR-memetics. I personally am trying to get off the cholesterol drug Pravachol, a statin compound, starting a few of weeks ago. Write me, and I'll let you know how it turns out. From the article...

"Fontana says ... evidence of "younger" hearts in people on calorie restriction, suggest that humans on CR have the same adaptive responses as did animals whose rates of aging were slowed by CR."

I think that it is time to look at the tannins in tobacco leaves. There may be other treasures lurking there too. As you may be aware there is ample public research into any possible beneficial compounds that may be obtained from tobacco leaves. The mechanisms are there waiting to be discovered. If you want to post them, just reply to me and I'd be delighted to host them.

The public establishment of prior art is a time-honed method of entering inventions into the public domain. We now have other methods at our disposal as well. If you are planning to establish prior art against future CR-memetic related patents, you might want to have a look at www.creativecommons.org. Perhaps it goes without saying at this point that you should please choose a license that provides for free and broad public access to your memetic.

In that way you will assure that the public health is served by anchoring them to the public common, where they cannot be exploited by those who would withhold them for their own profit. The DRM situation is precisely analogous to this. Can you imagine doing science in a world where your ability to read and write your data is filtered through secret protocols that are hidden from you? I recommend the Defective By Design campaign to fight the outrage of DRM, which is incompatible with the scientific pursuit.

http://www.defectivebydesign.org/